2010: accepted or in press

1. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N*. Blood pressure and hypertension are associated with seven loci showing male-specific interaction with age among the Japanese. Circulation. 2010, 121(21):2302-9. PMID: 20479155
2. Takeuchi F, Kashida M, Okazaki O, Tanaka Y, Fukuda S, Kashima T, Hosaka S, Hiroe M, Kimura S, Kato N*. Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients. Circ J. 2010, 74:977-82. PMID: 20339191
3. Taniguchi-Yanai K, Koike Y, Hasegawa T, Furuta Y, Serizawa M, Ohshima N, Kato N*, Yanai K*. Identification and characterization of glucocorticoid receptor-binding sites in the human genome. J Recept Signal Transduct Res. 2010, 30(2):88-105. PMID: 20163328
4. Takeuchi F, Katsuya T, Charkrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N*. Common variants at the GCK, GCKR, G6PC2-ABCB11,and MTNR1B lociare associatedwith fasting glucose in two Asian populations. Diabetologia. 2010, 53(2):299-308. PMID: 19937311

2009

5. Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N*. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes. 2009, 58(7):1690-9. PMID: 19401414
6. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Makino Y, Wakahara S, Inoki I, Miyamori I, Pinet F; the Genomic Disease Outcome Consortium (G-DOC) Study Investigators. Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blocker. Diabetes Care. 2009, 32(8):1485-90. PMID: 19509012
7. Takeuchi F, Nabika T, Isono M, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Yamori Y, Ogihara T, Kato N*. Evaluation of genetic loci influencing adult height in the Japanese population. J Hum Genet. 2009, 54(12):749-52. PMID: 19834501
8. Tsuchihashi-Makaya M, Serizawa M, Yanai K, Katsuya T, Takeuchi F, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environmental interaction regarding alcohol metabolizing enzymes in the Japanese general population. Hypertens Res. 2009, 32(3):207-13. PMID: 19262484
9. Fujimoto T, Miyasaka K, Koyanagi M, Tsunoda T, Baba I, Doi K, Ohta M, Kato N, Sasazuki T, Shirasawa S. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS ONE. 2009, 4:e4240. Epub 2009 Jan 21. PMID: 19156225
10. Tsuchihashi-Makaya M, Hamaguchi S, Kinugawa S, Yokota T, Goto D, Yokoshiki H, Kato N, Takeshita A, Tsutsui H; JCARE-CARD Investigators. Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J. 2009, 73(10):1893-900. PMID: 19644216
11. Dassanayake AS, Kasthuriratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, Makaya M, Mizoue T, Kato N, Wickremasinghe AR, de Silva HJ. Prevalence and risk factors for non-alcoholic fatty liver disease (NAFLD) among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009, 24(7):1284-8. PMID: 19476560
12. Morii T, Ohno Y, Kato N, Hirose H, Kawabe H, Hirao K, Eguchi T, Maruyama T, Hayashi M, Saito I, Yazaki Y, Saruta T. CD36 SNP is associated with variation in LDL-cholesterol in young Japanese men. Biomarkers. 2009, 14(4):207-12. PMID: 19489681
13. Tsuchihashi-Makaya M, Kato N, Chishaki A, Takeshita A, Tsutsui H. Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure. Circ J. 2009, 73(2):280-7. PMID: 19096191
14. Tsukahara T, Nakashima E, Watarai A, Hamada Y, Naruse K, Kamiya H, Nakamura N, Kato N, Hamajima N, Sekido Y, Niwa T, Tomita M, Oiso Y, Nakamura J. Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients. Diabetes Res Clin Pract. 2009, 84(2):179-86. PMID: 19269054
15. Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H. Fas Promoter Region Gene Polymorphism Is Associated With An Increased Risk For Myocardial Infarction. Hypertens Res. 2009, 32(4):261-4. PMID: 19262492
16. Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 2009 Mar;5(3):e1000433. Epub 2009 Mar 20. PMID: 19300499

2008

17. Kato N*, Miyata T, Tabara Y, Katsuya T, Yanai K, Hanada H, Kamide K, Nakura J, Kohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakayama T, Soma M, Hata A, Fujioka A, Kawano Y, Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara T, Sugano S, Miki T, Tomoike H. High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet. 2008, 17:617-27. PMID: 18003638
18. Ochiai Y, Liang YQ, Serizawa M, Kato N*. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. Physiol Genomics. 2008, 35:330-40. PMID: 18796534
19. Takeuchi F, Ochiai Y, Serizawa M, Yanai K, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q. J Hum Genet. 2008, 53:314-24. PMID: 18259684
20. Takeuchi F, Serizawa M, Kato N*. HapMap coverage for SNPs in the Japanese population. J Hum Genet. 2008, 53:96-9. PMID: 18043864
21. Serizawa M, Nabika T, Ochiai Y, Takahashi K, Yamaguchi S, Makaya M, Kobayashi S, Kato N*. Association between PRKCH gene polymorphisms and subcortical silent brain infarction. Atherosclerosis. 2008, 199:340-5. PMID: 18164711
22. Kato N*, Liang YQ, Ochiai Y, Birukawa N, Serizawa M, Jesmin S. Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. Hypertens Res. 2008, 31:1963-75. PMID: 19015604
23. Kato N*, Liang YQ, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. Eur J Pharmacol. 2008, 584:376-89. PMID: 18295756
24. Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics. 2008, 91:451-7. PMID: 18329245

2007

25. Takeuchi F, Yanai K, Inomata H, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search of type 2 diabetes susceptibility gene on chromosome 20q. Biochem Biophys Res Commun. 2007, 357:1100-6. PMID: 17466274
26. Jesmin S, Maeda S, Mowa CN, Zaedi S, Togashi H, Prodhan SH, Yamaguchi T, Yoshioka M, Sakuma I, Miyauchi T, Kato N. Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat. Eur J Pharmacol. 2007, 574:158-71. PMID: 17689527
27. Fujimoto T, Koyanagi M, Baba I, Nakabayashi K, Kato N, Sasazuki T, Shirasawa S. Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J Hum Genet. 2007, 52:978-84. PMID: 17934691
28. Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology. 2007, 148:2453-7. PMID: 17303661

2006

29. Konoshita T, Wakahara S, Mizuno S, Motomura M, Aoyama C, Makino Y, Kawai Y, Kato N, Koni I, Miyamori I, Mabuchi H. Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. Diabetes Care. 2006, 29:848-52. PMID: 16567826
30. Manabe N, Hoshino A, Liang YQ, Goto T, Kato N, Yamamoto K. Quantum dot as a drug tracer in vivo. IEEE Trans Nanobioscience. 2006, 5:263-7. PMID: 17181025
31. Takeuchi F, Yamamoto K. Effectiveness of realistic vaccination strategies for contact networks of various degree distributions. J Theor Biol. 2006, 243(1):39-47. PMID: 16860340

2005

32. Takeuchi F, Yanai K, Morii T, Ishinaga Y, Taniguchi-Yanai K, Nagano S, Kato N. Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. Genetics. 2005, 170:291-304. PMID: 15716494
33. Watanabe T, Iizuka Y, Liang Y-Q, Inomata H, Gotoda T, Yanai K, Isobe M, Kato N*. Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony Biochem Biophys Res Commun. 2005, 329: 879-87. PMID: 15752738
34. Inomata H, Watanabe T, Iizuka Y, Liang Y-Q, Mashimo T, Nabika T, Ikeda K, Yanai K, Gotoda T, Yamori Y, Isobe M, Kato N*. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Hypertens Res. 2005, 28: 273-81. PMID: 16097372

1. Takeuchi F, Katsuya T, Yamamoto K, Nabika T, Ranawaka U, Sugiyama T, Fujioka A, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Chakrewarthy S, Wickremasinghe R, and Kato N, for the NIBIO GWA Study and Ragama Health Study. Confirmation of eight loci associated with measures of obesity in two Asian populations with substantial ethnic heterogeneity. 27th annual scientific meeting of the Obesity Society, Washington DC, USA, October, 2009.
2. Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N for the NIBIO GWA Study. Ethnic diversity in fine mapping of the susceptibility loci G6PC2-ABCB11 for fasting glucose and CDKAL1 for type 2 diabetes. 59th annual meeting of the American Society of Human Genetics, Honolulu, USA, October, 2009.
3. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Kimura T, Fujii M, Makino Y, Wakahara S, Arakawa K, Inoki I, Miyamori I, Pinet P. Genetic Variant of the Renin Angiotensin System Influences Blood Pressure Response to Angiotensin Receptor Blocker. 19th European Meeting on Hypertension, Milan, Italy, June, 2009.
4. Kato N, Liang Y-Q, Ochiai Y, Serizawa M. Dissection of phenotypic traits associated with metabolic syndrome and positional cloning in the spontaneously hypertensive rat. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
5. Kato N, Liang Y-Q, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
6. Ochiai Y, Liang Y-Q, Serizawa M, Birukawa N, Jesmin S, Kato N. Exploration of adipose tissue transcriptome network triggered in vivo by an insulin sensitizing agent, pioglitazone. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
7. Serizawa M, Liang Y-Q, Yanai K, Ochiai Y, Birukawa N, Jesmin S, Kato N. Compartmentalization of genome network downstream of the glucocorticoid receptor in cultured insulinoma cells and hepatoma cell. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
8. Manabe N, Hoshino A, Liang Y-Q, Fujioka K, Kato N, Yamamoto K. Quantum dot as a drug-tracer in vivo. Third International Conference on Advanced Materials and Nanotechnology, Wellington, New Zealand, February, 2007.
9. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. American Heart Association, Scientific Sessions 2006, Chicago, IL, November, 2006.
10. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Systematic expression profiling in the major end-organs after pharmacological intervention. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
11. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
12. Kato N, Yanai K, Makaya M, Nabika T, Katsuya T, Fujioka A, Yasuda K, Yamori Y, Kobayashi S, Ogihara T, Yazaki Y. Integrative large-scale candidate gene analysis of atherosclerotic diseases. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
13. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
14. Kohara Y, Inomata H, Liang Y-Q, Y Ochiai Y, Serizawa M, Yanai K, Kato N. Unraveling genetic susceptibility by constructing 14 consomic strains derived from the spontaneously hypertensive rat strains. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
15. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the japanese general population. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
16. Inomata H, Yanai K, Nabika T, Nagano S, Isobe M, Kobayashi S, Kato N. Large-scale genetic analysis of stroke in the Japanese. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
17. Inomata H, Liang YQ, Yanai K, Isobe M, Kato N. Unraveling genetic susceptibility by the construction of eight consomic strains derived from the stroke-prone spontaneously hypertensive rat. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
18. Manabe N, Hoshino A, Liang Y-Q, Goto T Kato N, Yamamoto K. Quantum dots conjugated with captoril while remained effective in vivo. 2nd International Conference on Advanced Materials and Nanotechnology, Queenstown, February, 2005.