Research Achievements

I. Publications (*corresponding author)

2011

  1. Cho YS, Chen C-H, Hu C, Long J, Ong RTH, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang Y-C, Kwak SH, Ma RCW, Yamamoto K, Adair LS, Aung T, Cai Q, Chang L-C, Chen Y-T, Gao Y, Hu FB, Kim H-L, Kim S, Kim YJ, Lee JJ-M, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, NgDP-K, Tay WT, Tsai F-J, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang T-J, Bao Y, Hedman AK, P Morris AP, McCarthy MI, DIAGRAM consortium36, MuTHER consortium36, Takayanagi R, Park KS, Jia W, Chuang L-M, ChanJCN, Maeda S, Kadowaki T, Lee J-Y, Wu J-Y, TeoYY, Tai ES, Shu XO, Mohlke KL, Kato N, Han B-G, Seielstad M. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature Genet. 2011 Dec 11. [Epub ahead of print]. PMID: 22158537
  2. Li H, Kilpelainen T, Liu C, Zhu J, Liu Y, Hu C, Yang Z, Bao W, Cha S, Wu Y, Yang T-L, Sekine A, Choi BY, Yajnik CS, Zhou D, Takeuchi F, Yamamoto K, Chan JC, Mani KR, Been LF, Imamura M, Nakashima E, Lee N, Fujisawa T, Karasawa S, Wen W, Lu W, Chang Y-C, Xiang Y-B, Gao Y, Liu S, Song Y, Kwak SH, Shin HD, Park KS, Fall C, Kim JY, Sham PC, Lam KSL, Zheng W, Shu XO, Deng H-W, Ikegami H, Sanghera DK, Chuang L-M, Liegang Liu, Hu R, Kim Y-M, Daimon M, Hotta K, Jia W, Kooner JS, Chambers JC, Chandak GR, Ma RC, Maeda S, Dorajoo R, Yokota M, Takayanagi R, Kato N, Lin X, Loos RJF. Association of genetic variation in FTO with risk of obesity and type 2 diabetes in up to 96,551 East and South Asians. Diabetologia. 2011 Nov 23. [Epub ahead of print] PMID: 22109280
  3. Takeuchi F, Yokota M, Yamamoto K, Nakashima E, Katsuya T, Asano H, Isono M, Nabika T, Sugiyama T, Fujioka A, Awata N, Ohnaka K, Nakatochi M, Kitajima H, Rakugi H, Nakamura J, Ohkubo T, Imai Y, Shimamoto K, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N*. Genome-wide association study of coronary artery disease in the Japanese. Eur J Hum Genet. 2011 Oct 5. doi: 10.1038/ejhg.2011.184. [Epub ahead of print] PMID: 21971053
  4. Kato N*, Takeuchi F, Tabara Y, Kelly TN, Go MJ, Sim X, Tay WT, Chen CH, Zhang Y, Yamamoto K, Katsuya T, Yokota M, Kim YJ, Ong RT, Nabika T, Gu D, Chang LC, Kokubo Y, Huang W, Ohnaka K, Yamori Y, Nakashima E, Jaquish CE, Lee JY, Seielstad M, Isono M, Hixson JE, Chen YT, Miki T, Zhou X, Sugiyama T, Jeon JP, Liu JJ, Takayanagi R, Kim SS, Aung T, Sung YJ, Zhang X, Wong TY, Han BG, Kobayashi S, Ogihara T, Zhu D, Iwai N, Wu JY, Teo YY, Tai ES, Cho YS, He J. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nature Genet. 2011, Jun;43(6):531-8. PMID: 21572416
  5. Kooner JS*, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, Been LF, Chia K-S, Dimas AS, Hassanali N, Jafar T, Jowett JBM, Venkatesan R, Rees SD, Takeuchi F, Young R, Aung T, Basit A, Chidambaram M, Das D, Grunberg E, Hedman AK, Hydrie ZI, Islam M, Khor C-C, Kowlessur S, Kristensen MM, Liju S, Lim W-Y, Matthews DR, Liu J, Morris AP, Nica AC, Pinidiyapathirage JM, Prokopenko I, Rasheed A, Samuel M, Shah N, Shera AS, Small KS, Suo C, Wickremasinghe AR, Wong TY, Yang M, Zhang F, DIAGRAM, MuTHER, Abecasis GR, Barnett AH, Caulfield M, Deloukas P, Frayling T, Froguel P, Kato N, Katulanda P, Kelly MA, Liang J, Mohan V, Sanghera DK, Scott J, Seielstad M, Zimmet PZ, Elliott P, Teo YY, McCarthy MI, Danesh J, Tai ES, Chambers JC*. Genome-wide association study in people of South Asian ancestry identifies six novel susceptibility loci for Type 2 Diabetes. Nature Genet. Aug 28;43(10):984-9 PMID: 21874001
  6. Takeuchi F*, Kobayashi S, Ogihara T, Fujioka A, Kato N. Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants. Genome Res. 2011, Jul;21(7):1122-30 PMID: 21441355
  7. Njelekela M, Muhihi A*, Mpembeni R, Masesa Z, Kitamori K, Mori-Yamori M, Kato N, Mtabaji J, Yamori Y. Prevalence of Cardiovascular Disease Risk Factors among Young and Middle-age Men in Urban Mwanza, Tanzania. J Public Health. Accepted.
  8. Takeuchi F, Yamamoto K, Katsuya T, Nabika T, Sugiyama T, Fujioka A, Isono M, Ohnaka K, Fujisawa T, Nakashima E, Ikegami H, Nakamura J, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Takayanagi R, Kato N*. Association of obesity susceptibility genetic variants with type 2 diabetes in the Japanese. Diabetologia. 2011, 54(6):1350-9. PMID: 21369819
  9. Dassanayake AS, Kasturiratne A, Niriella MA, Kalubovila U, Rajindrajith S, De Silva AP, Kato N, Wickremasinghe R and de Silva J*. Prevalence of acanthosis nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome. BMC Research Notes. 2011, 4(1):25. PMID: 21276250
  10. Sasawatari S, Okamura T, Kasumi E, Tanaka-Furuyama K, Yanobu-Takanashi R, Shirasawa S, Kato N, Toyama-Sorimachi N*. The solute carrier family 15A4 regulates TLR9 and NOD1 functions in the innate immune system and promotes colitis in mice. Gastroenterology. 2011, 140(5):1513-25. PMID: 21277849
  11. Takeuchi F, Isono M, Nabika T, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Ogihara T, Yamori Y, Fujioka A, Kato N*. Confirmation of ALDH2 as a major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in Japanese. Circ J. 2011, 75(4):911-8. PMID: 21372407

2010

  1. Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S. Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis. PLoS One. 2010 Dec 9;5(12):e15553. PMID: 21151568
  2. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N*. Blood pressure and hypertension are associated with seven loci showing male-specific interaction with age among the Japanese. Circulation. 2010, 121(21):2302-9. PMID: 20479155
  3. Takeuchi F, Kashida M, Okazaki O, Tanaka Y, Fukuda S, Kashima T, Hosaka S, Hiroe M, Kimura S, Kato N*. Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients. Circ J. 2010, 74:977-82. PMID: 20339191
  4. Taniguchi-Yanai K, Koike Y, Hasegawa T, Furuta Y, Serizawa M, Ohshima N, Kato N*, Yanai K*. Identification and characterization of glucocorticoid receptor-binding sites in the human genome. J Recept Signal Transduct Res. 2010, 30(2):88-105. PMID: 20163328
  5. Takeuchi F, Katsuya T, Charkrewarthy S, Yamamoto K, Fujioka A, Serizawa M, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N*. Common variants at the GCK, GCKR, G6PC2-ABCB11,and MTNR1B lociare associatedwith fasting glucose in two Asian populations. Diabetologia. 2010, 53(2):299-308. PMID: 19937311

2009

  1. Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N*. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes. 2009, 58(7):1690-9. PMID: 19401414
  2. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Makino Y, Wakahara S, Inoki I, Miyamori I, Pinet F; the Genomic Disease Outcome Consortium (G-DOC) Study Investigators. Genetic Variant of the Renin-Angiotensin System and Diabetes Influences Blood Pressure Response to Angiotensin Receptor Blocker. Diabetes Care. 2009, 32(8):1485-90. PMID: 19509012
  3. Takeuchi F, Nabika T, Isono M, Katsuya T, Sugiyama T, Yamaguchi S, Kobayashi S, Yamori Y, Ogihara T, Kato N*. Evaluation of genetic loci influencing adult height in the Japanese population. J Hum Genet. 2009, 54(12):749-52. PMID: 19834501
  4. Tsuchihashi-Makaya M, Serizawa M, Yanai K, Katsuya T, Takeuchi F, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environmental interaction regarding alcohol metabolizing enzymes in the Japanese general population. Hypertens Res. 2009, 32(3):207-13. PMID: 19262484
  5. Fujimoto T, Miyasaka K, Koyanagi M, Tsunoda T, Baba I, Doi K, Ohta M, Kato N, Sasazuki T, Shirasawa S. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS ONE. 2009, 4:e4240. Epub 2009 Jan 21. PMID: 19156225
  6. Tsuchihashi-Makaya M, Hamaguchi S, Kinugawa S, Yokota T, Goto D, Yokoshiki H, Kato N, Takeshita A, Tsutsui H; JCARE-CARD Investigators. Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J. 2009, 73(10):1893-900. PMID: 19644216
  7. Dassanayake AS, Kasthuriratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, Makaya M, Mizoue T, Kato N, Wickremasinghe AR, de Silva HJ. Prevalence and risk factors for non-alcoholic fatty liver disease (NAFLD) among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009, 24(7):1284-8. PMID: 19476560
  8. Morii T, Ohno Y, Kato N, Hirose H, Kawabe H, Hirao K, Eguchi T, Maruyama T, Hayashi M, Saito I, Yazaki Y, Saruta T. CD36 SNP is associated with variation in LDL-cholesterol in young Japanese men. Biomarkers. 2009, 14(4):207-12. PMID: 19489681
  9. Tsuchihashi-Makaya M, Kato N, Chishaki A, Takeshita A, Tsutsui H. Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure. Circ J. 2009, 73(2):280-7. PMID: 19096191
  10. Tsukahara T, Nakashima E, Watarai A, Hamada Y, Naruse K, Kamiya H, Nakamura N, Kato N, Hamajima N, Sekido Y, Niwa T, Tomita M, Oiso Y, Nakamura J. Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients. Diabetes Res Clin Pract. 2009, 84(2):179-86. PMID: 19269054
  11. Hanasaki H, Takemura Y, Fukuo K, Ohishi M, Onishi M, Yasuda O, Katsuya T, Awata N, Kato N, Ogihara T, Rakugi H. Fas Promoter Region Gene Polymorphism Is Associated With An Increased Risk For Myocardial Infarction. Hypertens Res. 2009, 32(4):261-4. PMID: 19262492
  12. Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 2009 Mar;5(3):e1000433. Epub 2009 Mar 20. PMID: 19300499

2008

  1. Kato N*, Miyata T, Tabara Y, Katsuya T, Yanai K, Hanada H, Kamide K, Nakura J, Kohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakayama T, Soma M, Hata A, Fujioka A, Kawano Y, Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara T, Sugano S, Miki T, Tomoike H. High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet. 2008, 17:617-27. PMID: 18003638
  2. Ochiai Y, Liang YQ, Serizawa M, Kato N*. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. Physiol Genomics. 2008, 35:330-40. PMID: 18796534
  3. Takeuchi F, Ochiai Y, Serizawa M, Yanai K, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q. J Hum Genet. 2008, 53:314-24. PMID: 18259684
  4. Takeuchi F, Serizawa M, Kato N*. HapMap coverage for SNPs in the Japanese population. J Hum Genet. 2008, 53:96-9. PMID: 18043864
  5. Serizawa M, Nabika T, Ochiai Y, Takahashi K, Yamaguchi S, Makaya M, Kobayashi S, Kato N*. Association between PRKCH gene polymorphisms and subcortical silent brain infarction. Atherosclerosis. 2008, 199:340-5. PMID: 18164711
  6. Kato N*, Liang YQ, Ochiai Y, Birukawa N, Serizawa M, Jesmin S. Candesartan-induced gene expression in five organs of stroke-prone spontaneously hypertensive rats. Hypertens Res. 2008, 31:1963-75. PMID: 19015604
  7. Kato N*, Liang YQ, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. Eur J Pharmacol. 2008, 584:376-89. PMID: 18295756
  8. Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics. 2008, 91:451-7. PMID: 18329245

2007

  1. Takeuchi F, Yanai K, Inomata H, Kuzuya N, Kajio H, Honjo S, Takeda N, Kaburagi Y, Yasuda K, Shirasawa S, Sasazuki T, Kato N*. Search of type 2 diabetes susceptibility gene on chromosome 20q. Biochem Biophys Res Commun. 2007, 357:1100-6. PMID: 17466274
  2. Jesmin S, Maeda S, Mowa CN, Zaedi S, Togashi H, Prodhan SH, Yamaguchi T, Yoshioka M, Sakuma I, Miyauchi T, Kato N. Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat. Eur J Pharmacol. 2007, 574:158-71. PMID: 17689527
  3. Fujimoto T, Koyanagi M, Baba I, Nakabayashi K, Kato N, Sasazuki T, Shirasawa S. Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J Hum Genet. 2007, 52:978-84. PMID: 17934691
  4. Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology. 2007, 148:2453-7. PMID: 17303661

2006

  1. Konoshita T, Wakahara S, Mizuno S, Motomura M, Aoyama C, Makino Y, Kawai Y, Kato N, Koni I, Miyamori I, Mabuchi H. Tissue gene expression of renin-angiotensin system in human type 2 diabetic nephropathy. Diabetes Care. 2006, 29:848-52. PMID: 16567826
  2. Manabe N, Hoshino A, Liang YQ, Goto T, Kato N, Yamamoto K. Quantum dot as a drug tracer in vivo. IEEE Trans Nanobioscience. 2006, 5:263-7. PMID: 17181025
  3. Takeuchi F, Yamamoto K. Effectiveness of realistic vaccination strategies for contact networks of various degree distributions. J Theor Biol. 2006, 243(1):39-47. PMID: 16860340

2005

  1. Takeuchi F, Yanai K, Morii T, Ishinaga Y, Taniguchi-Yanai K, Nagano S, Kato N. Linkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. Genetics. 2005, 170:291-304. PMID: 15716494
  2. Watanabe T, Iizuka Y, Liang Y-Q, Inomata H, Gotoda T, Yanai K, Isobe M, Kato N*. Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony Biochem Biophys Res Commun. 2005, 329: 879-87. PMID: 15752738
  3. Inomata H, Watanabe T, Iizuka Y, Liang Y-Q, Mashimo T, Nabika T, Ikeda K, Yanai K, Gotoda T, Yamori Y, Isobe M, Kato N*. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Hypertens Res. 2005, 28: 273-81. PMID: 16097372

II. Presentations at International Scientific Meetings

  1. Matsushita Y, Kishimoto M, Takahashi Y, Kanagawa S, Noda M, Thai SP, Ngoc QN, Hong HPT, Doan LD, Lan VN, Zeng Z-P, Wickremasinghe AR, Naruse M, Kato N, Kajio H. The Cutoff Levels of Waist Circumference for Predicting the Presence of the Clustering of Metabolic Risk Factors in some Asian Populations. IDF World Diabetes Congress 2011, Dubai, UAE, December, 2011.
  2. Horikoshi M, Wiltshire S, Kato N, Asimit J, Rayner N, Robertson N, Takeuchi F, Mahajan A, Teo Y-Y, Zeggini E, Morris A, McCarthy M, T2D-GENES. Trans-ethnic fine-mapping of Type 2 Diabetes susceptibility loci using a “Cosmopolitan Ereference panel for imputation. 61st annual meeting of the American Society of Human Genetics and the International Congress of Human Genetics 2011, Montreal, Canada, Oct 14, 2011.
  3. Kato N. GWAS of hypertension-associated disease in the Japanese. 20th KOGO Conference. Osong, Korea, September, 2011.
  4. Horikoshi M, Kato N, Wiltshire S, Asimit J, Rayner NW, Robertson N, Takeuchi F, Teo YY, Zeggini, E, McCarthy M, Morris A, T2D-GENES Consortium. Trans-Ethnic Fine-Mapping of T2D Susceptibility Loci. ADA Annual Meeting 2011, San Diego, USA, June, 2011.
  5. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. 5th Oriental Congress of Cardiology, Shanghai, China, May, 2011.
  6. Kato N. Genome-wide exploration of genetic susceptibility to hypertension and associated diseases. The National University of Singapore, Advanced genomics symposium, Singapore, February, 2011.
  7. Takeuchi F, Kato N. Testing heterogeneity of quantitative trait variance among genotype classes guides fine mapping of association signals. 60th annual meeting of the American Society of Human Genetics, Washington DC, USA, November, 2010.
  8. Kato N. Genetic susceptibility to diabetes and associated diseases in the Japanese. 8th IDF WPR Congress. Busan, Korea, October, 2010.
  9. Kato N. Genome-wide exploration of genetic susceptibility to cardiometabolic diseases. International Congress of Pathophysiology & International SHR Symposium 2010. Montreal, Canada, September, 2010.
  10. Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N. Blood pressure and hypertension are associated with seven loci in the Japanese population. 23rdrd Scientific Meeting International Society of Hypertension. Vancouver, Canada, September, 2010.
  11. Kato N. Genetic susceptibility to cardiovascular disease and its risk factors in the Japanese. 19th KOGO Conference. Seoul, Korea, September, 2010.
  12. Kato N. Risk of myocardial infarction and stroke among Asians. 10th South East Asia Regional Scientific Meeting of the International Epidemiological Association, Colombo, Sri Lanka, May, 2010.
  13. Takeuchi F, Katsuya T, Yamamoto K, Nabika T, Ranawaka U, Sugiyama T, Fujioka A, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Chakrewarthy S, Wickremasinghe R, and Kato N, for the NIBIO GWA Study and Ragama Health Study. Confirmation of eight loci associated with measures of obesity in two Asian populations with substantial ethnic heterogeneity. 27th annual scientific meeting of the Obesity Society, Washington DC, USA, October, 2009.
  14. Takeuchi F, Katsuya T, Chakrewarthy S, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Nabika T, Kasturiratne A, Yamaguchi S, Kono S, Takayanagi R, Yamori Y, Kobayashi S, Ogihara T, de Silva A, Wickremasinghe R, Kato N for the NIBIO GWA Study. Ethnic diversity in fine mapping of the susceptibility loci G6PC2-ABCB11 for fasting glucose and CDKAL1 for type 2 diabetes. 59th annual meeting of the American Society of Human Genetics, Honolulu, USA, October, 2009.
  15. Konoshita T, Kato N, Fuchs S, Mizuno S, Aoyama C, Motomura M, Kimura T, Fujii M, Makino Y, Wakahara S, Arakawa K, Inoki I, Miyamori I, Pinet P. Genetic Variant of the Renin Angiotensin System Influences Blood Pressure Response to Angiotensin Receptor Blocker. 19th European Meeting on Hypertension, Milan, Italy, June, 2009.
  16. Kato N, Liang Y-Q, Ochiai Y, Serizawa M. Dissection of phenotypic traits associated with metabolic syndrome and positional cloning in the spontaneously hypertensive rat. The 22nd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  17. Kato N, Liang Y-Q, Ochiai Y, Jesmin S. Systemic evaluation of gene expression changes in major target organs induced by atorvastatin. The 22ndnd Scientific Meeting International Society of Hypertension, Berlin, Germany, June, 2008.
  18. Ochiai Y, Liang Y-Q, Serizawa M, Birukawa N, Jesmin S, Kato N. Exploration of adipose tissue transcriptome network triggered in vivo by an insulin sensitizing agent, pioglitazone. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  19. Serizawa M, Liang Y-Q, Yanai K, Ochiai Y, Birukawa N, Jesmin S, Kato N. Compartmentalization of genome network downstream of the glucocorticoid receptor in cultured insulinoma cells and hepatoma cell. 21st International Mammalian Genome Conference, Kyoto, Japan, October, 2007.
  20. Manabe N, Hoshino A, Liang Y-Q, Fujioka K, Kato N, Yamamoto K. Quantum dot as a drug-tracer in vivo. Third International Conference on Advanced Materials and Nanotechnology, Wellington, New Zealand, February, 2007.
  21. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. American Heart Association, Scientific Sessions 2006, Chicago, IL, November, 2006.
  22. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Systematic expression profiling in the major end-organs after pharmacological intervention. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  23. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the Japanese general population. 12th International SHR Symposium, Kyoto, Japan, October, 2006.
  24. Kato N, Yanai K, Makaya M, Nabika T, Katsuya T, Fujioka A, Yasuda K, Yamori Y, Kobayashi S, Ogihara T, Yazaki Y. Integrative large-scale candidate gene analysis of atherosclerotic diseases. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  25. Ochiai Y, Liang Y-Q, Serizawa M, Yanai K, Kato N. Dynamic changes of the renin-angiotensin and associated systems in the rat after pharmacological and dietary interventions in vivo. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  26. Kohara Y, Inomata H, Liang Y-Q, Y Ochiai Y, Serizawa M, Yanai K, Kato N. Unraveling genetic susceptibility by constructing 14 consomic strains derived from the spontaneously hypertensive rat strains. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  27. Makaya M, Yanai K, Katsuya T, Fujioka A, Yamori Y, Ogihara T, Kato N. Gene-environment interaction regarding ethanol metabolizing enzymes in the japanese general population. 21st Scientific Meeting of the International Society of Hypertension, Fukuoka, October, 2006.
  28. Inomata H, Yanai K, Nabika T, Nagano S, Isobe M, Kobayashi S, Kato N. Large-scale genetic analysis of stroke in the Japanese. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  29. Inomata H, Liang YQ, Yanai K, Isobe M, Kato N. Unraveling genetic susceptibility by the construction of eight consomic strains derived from the stroke-prone spontaneously hypertensive rat. International Stroke Conference 2006, Kissimmee, FL, February, 2006.
  30. Manabe N, Hoshino A, Liang Y-Q, Goto T Kato N, Yamamoto K. Quantum dots conjugated with captoril while remained effective in vivo. 2nd International Conference on Advanced Materials and Nanotechnology, Queenstown, February, 2005.